EDUCATION

Nov 2017 – Mar 2021: PhD. in Molecular and Cellular Biology Faculty of Medicine, University of Paris-Saclay, 91190 Gif-sur-Yvette, France. Thesis topic: Regulation of the Akt/mTORC1 Pathway by HIV Transcriptional Activator Tat in B Cells.

Oct 2012 – Jul 2014: M.S. in Biomedical Science, Faculty of Science and Technology, University of Rouen Normandy, 76130 Mont-Saint-Aignan, France. Thesis topic: Study of effect of combined treatment of retinoic acid and arsenic trioxide on the differentiation of neuroblastoma cells.

Sep 2006 – Jun 2011: B.S. in Pharmacy, Faculty of Pharmacy, Xinjiang Medical University, Urumqi, Xinjiang 830011, China

RESEARCH AND WORK EXPERIENCE

March 2021 to present: Postdoctoral Fellow, School of Medicine, Nazarbayev University, Nur-Sultan (Astana), Kazakhstan

Apr 2016 – Jan 2017: Medical Device Assembler, Branch of HeartStitch company (USA) at Nazarbayev University, Nur-Sultan (Astana), Kazakhstan

Aug 2015 – Mar 2016: Research Assistant, School of Science and Technology, Nazarbayev University, Nur-Sultan (Astana), Kazakhstan

Jan 2014 – Jul 2014: Master thesis research program, Faculty of Medicine, University of Rouen Normandy, 76130 Mont-Saint-Aignan, France

ORGANIZATION OF SCIENTIFIC EVENTS

2021: Online Workshop – Vaccine Design for Emerging Viruses, 04 December 2021

ORAL PRESENTATIONS

2019: 9th Scientific days of CFATG In collaboration with the German and Swiss networks for Autophagy Research, 20-22th of November 2019, Obernai, France

2020: International Conference on Innovative Solutions: Cancer, Aging and Genetic diseases, Worldwide Live Remote Conference, 27, 28, 29th of October & 8th of December 2020

HONORS & AWARDS

2020: ICIS 2020 (International Conference on Innovative Solutions: Cancer, Aging and Genetic diseases) prize winner

2019: 9th Scientific days of CFATG (Club Francophone de l’AuTophaGie) Travel Grant, Obernai, France

2017: French Government Scholarship for PhD

2011: Outstanding graduate Award, Xinjiang Medical University, Urumqi, Xinjiang

TECHNICAL SKILLS

Biochemistry: Immunoprecipitation (IP), Western blotting, Real-time PCR, ELISA, Immunohistochemistry, Protein purification, Helicase assay

Genetics: Gene cloning, Gene overexpression

Cell biology: Flow Cytometry, Cell-based assays (CCK-8, MTT, colony formation), Cellular immunological assays

Bioinformatics: Immunoinformatics tools (T and B cell epitope prediction, immune simulation, vaccine construction), Tools for phylogenetics (BEAST, FastTree, IQ tree, MEGA, FigTree)

Mouse models: Animal surgery, Immunology mouse model, xenograft mouse model

1. Burkitkan Akbay, Syed Hani Abidi, Mahmoud A. A. Ibrahim, Zhussipbek Mukhatayev, Syed Ali. Multi-Subunit SARS-CoV-2 Vaccine Design Using Evolutionarily Conserved T- and B- Cell Epitopes. Vaccines 2021, 9, 702
2. Burkitkan Akbay, Diego Germini, Amangeldy K Bissenbaev, Yana R Musinova, Evgeny V Sheval, Yegor Vassetzky, Svetlana Dokudovskaya. HIV-1 Tat Activates Akt/mTORC1 Pathway and AICDA Expression by Downregulating Its Transcriptional Inhibitors in B Cells. International Journal of Molecular Sciences 2021, 22 (4), 1588
3. Burkitkan Akbay, Anna Shmakova, Yegor Vassetzky, Svetlana Dokudovskaya. Modulation of mTORC1 Signaling Pathway by HIV-1.Cells 2020, 28, 9(5),1090
4. MA Gorbacheva, MA Tikhomirova, DM Potashnikova, B Akbay, EV Sheval, YR Musinova. Production of Stable Cell Lines on the Basis of the Cultured RPMI 8866 B-Cells with Constant and Inducible Expression of the Human Immunodeficiency Virus Tat Protein. Russian Journal of Developmental Biology 2019, 50 (5), 275-280
5. Yingqiu Xie, Ayan A Nurkesh, Nazgul Ibragimova, Zhuldyz Zhanzak, Aizhan Meyerbekova, Zhanna Alexeyeva, Aiya Yesbolatova, Madina Satayeva, Aidana Mustafa, Limara Manarbek, Aisulu Maipas, Akerke Altaikyzy, Zhibek Keneskhanova, Burkitkan Akbay, Zhenbang Chen. Systematic analysis of NLMP suggests nuclear localization of RTK/MET kinases resemble cancer cell clearance. Journal of Experimental & Clinical Cancer Research 2019, 38 (1), 1-12

Biology for non-science majors

Modern Biology laboratory I

Introduction to Microbiology Laboratory