Research Interest
Dr. Kanayeva established research direction in the field of biosensors and biodetection at NU, which represents a promising option for developing reliable, simple, and affordable tools for the effective detection of pathogens and cancer biomarkers.
Dr. Damira Kanayeva joined Nazarbayev University in 2011. Since then she has been actively involved in teaching, research, and service as well. Dr. Kanayeva established research direction in the field of biosensors and biodetection at NU, which represents a promising option for developing reliable, simple, and affordable tools for the effective detection of pathogens. She is an advisor of several undergraduate and graduate students, who are actively pursuing their degrees in the field of biomedical engineering. Undergraduate team of biology students supervised by Dr. Kanayeva received bronze (2014) and silver (2015) medals in a worldwide synthetic biology competition iGEM (International Genetically Engineered Machine). She is the PI of ongoing state target program as well as grants. In a short period, Dr. Kanayeva and her colleagues managed to establish a high-potential research center, Interdisciplinary Instrumental Center, which became a home for many bright researchers from various fields. She is also a member of professional societies (American Society for Microbiology, International Society for Optics and Photonics, and others) and honorary organizations such as Phi Kappa Phi (USA). She received her Ph.D. degree in cell and molecular biology from University of Arkansas (USA) with biosensors being a primary focus of her studies. Currently, Dr. Kanayeva holds position of an assistant professor in the Department of Biology, School of Science and Technology at Nazarbayev University.
PATENTS
Kanayeva D, Sypabekova M, Bekmurzayeva A, Li Y. 2019. Aptamers for determining bacterial cell Mycobacterium tuberculosis based on secreted protein MPT64, composition containing DNA aptamer and method of detecting mycobacteria in a clinical sample. IPC No. C12P 19/34 (2006.01), C12Q 1/00 (2006.01), Ministry of Justice of the Republic of Kazakhstan, Patent No. 33639, Oct 30, 2017.
PUBLICATIONS
Bekmurzayeva, A., Dukenbayev, K., Azevedo , H., Marsili, E., Tosi, D., & Kanayeva, D. (2020). Optimizing silanization to functionalize stainless steel wire: towards breast cancer stem cell isolation. Materials, 13( 3693). https://doi.org/10.3390/ma13173693
Sypabekova, M., Dukenbayev, K., Tsepke, A., Akisheva, A., Oralbayev, N., & Kanayeva, D. (2019). An aptasensor for the detection of Mycobacterium tuberculosis secreted immunogenic protein MPT64 in clinical samples towards tuberculosis detection. Scientific Reports, 9(1), [16273]. https://doi.org/10.1038/s41598-019-52685-6
Sypabekova, M., Jolly, P., Estrela, P., Kanayeva, D. Electrochemical aptasensor using optimized surface chemistry for the detection of Mycobacterium tuberculosis secreted protein MPT64 in human serum. Biosens Bioelectron. 2019 Jan 1; 123: 141-151. doi:10.1016/j.bios.2018.07.053. Epub 2018 Jul 26.
Bekmurzayeva, A., Duncanson, W., Azevedo, H., Kanayeva, D. Surface modification of stainless steel for biomedical applications: Revisiting a century-old material. Mater Sci & Eng C. 2018 Dec 1; 93: 1073-1089. doi:10.1016/j.msec.2018.08.049. Epub 2018 Aug 24. Review.
Islamov, M., Sypabekova, M., Kanayeva, D., Rojas-Solórzano, L. CFD modeling of chamber filling in a micro-biosensor for protein detection. Biosensors (Basel). 2017 Oct 3; 7(4), pii: E45. doi: 10.3390/bios7040045.
Sypabekova, M., Bekmurzayeva, A., Wang, R., Li, Y., Nogues, C., Kanayeva, D. Selection, characterization, and application of DNA aptamers for detection of Mycobacterium tuberculosis secreted protein MPT64. Tuberculosis (Edinb). 2017 May; 104: 70-78. doi: 10.1016/j.tube.2017.03.004. Epub 2017 Mar 18.
Bekmurzayeva, A., Sypabekova, M., Kanayeva, D. Tuberculosis diagnosis using immunodominant, secreted antigens of Mycobacterium tuberculosis. Tuberculosis (Edinb). 2013 Jul; 93 (4): 381-8. doi: 10.1016/j.tube.2013.03.003. Epub 2013 Apr 17. Review.
Kanayeva, D., Bekniyazov, I., Ashikbayeva, Z. Detection of tuberculosis using biosensors: recent progress and future trends. Sensors & Transducers. 2013 149 (2): 166-173.
Kanayeva, D., Wang, R., Rhoads, D., Erf, G., Slavik, M., Tung, S., Li, Y. Efficient separation and sensitive detection of Listeria monocytogenes using an impedance immunosensor based on magnetic nanoparticles, a microfluidic chip, and an interdigitated microelectrode. J Food Prot. 2012 Nov; 75 (11): 1951-9. doi: 10.4315/0362-028X.JFP-11-516.
Wang, R., Dong, W., Ruan, C., Kanayeva, D., Lassiter, K., Li, Y. TiO2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes. Nano Lett. 2008 Sep; 8 (9): 2625-31. doi: 10.1021/nl080366q. Epub 2008 Aug 21.
UG courses
BIOL 101 Biology for non-Science majors
BIOL 120 Modern Biology II with Laboratory
BIOL 241 Special Topics in Synthetic Biology
BIOL 299 Biology Internship
BIOL 210/305 Introduction to Microbiology with Laboratory
BIOL 450 Food Microbiology
BIOL 450L Food Microbiology Laboratory
BIOL 492 Directed Study in Biology
CHEM 92 Survey of Environmental Sciences for Non-Science Majors
G courses
BIOL 560 Molecular Biology of Prokaryotic Cells
BIOL 600 Graduate Seminar Series