EDUCATION

11/10                      Teaching qualification: Venia legendi (Habilitation) in Experimental Medicine,

                                     University Medical Center Ulm, Germany

03/04 to 03/06        Postdoctoral Research Fellow, Stanford University School of Medicine,

                                     Stanford, CA, USA

01/01 to 01/04         Ph.D. Immunology, University of Tübingen, Germany

1997 to 2000            M.S. (Diplom) in Biology, University of Tübingen, Germany

1993 to 1997            B.S. (Vordiplom) in Biology, University of Freiburg, Germany

RESEARCH EXPERIENCE AND PREVIOUS EMPLOYMENT

01/18 to present       Associate Professor

Dept. Biology, School of Science and Technology, Nazarbayev University, Astana, Kazakhstan, Immunology, Tumor Immunology

09/13 to 12/17          Laboratory Head

Principle Investigator, Dept. Neurosurgery, Ulm University Medical Centre, Ulm, Germany, Tumor Immunology

11/13 to 09/16          Visiting Professor

Humboldt Award, Poland/Germany, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland, Immunology, Immunosenescence

10/12 to 06/13          Visiting Professor

Dept. Chemistry, University of Gdansk, Gdansk, Poland and Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland, stipend DAAD, Immunology

07/11 to present   Extraordinary Member of the University Medical Center Ulm (Habilitation, Privatdozent), Ulm University, Ulm, Germany, Experimental Medicine

10/06 to 06/11          Team Leader

Dept. Internal Medicine I, University Medical Center Ulm, Ulm, Germany, Autoimmunity

03/04 to 03/06          Postdoctoral Research Fellow, stipend DFG

Division of Pediatric Immunology and Transplantation Medicine, Stanford University School of Medicine, Stanford, CA, USA, Immunology, Biochemistry

01/01 to 01/04          Ph.D. in Immunology, University of Tübingen, Germany

Medical and Natural Sciences Research Center (MNF), University of Tübingen, Tübingen, Germany, Immunology, Autoimmunity

05/00 to 12/00          M.S. (Diplom) in Biology

Medical and Natural Sciences Research Center (MNF), University of Tübingen, Tübingen, Germany

12/98 to 03/00          Scientific Assistant

Max-Planck-Institute for Developmental Biology (MPI), Tübingen, Germany, Axon guidance

MEMBER OF THE EDITORIAL BOARD

PubMed

Google Scholar

Recent Publications

1. Zhadyra Mustafa, Hubert Kalbacher, and Timo Burster. Occurrence of a novel cleavage site for cathepsin G adjacent to the polybasic sequence within the proteolytically sensitive activation loop of the SARS-CoV-2 Omicron variant: The amino acid substitution N679K and P681H of the spike protein. PlosOne. IF: 3.24. SJR: 0.99, Q1, in press
2. Pengfei Xu, Mike-Andrew Westhoff, Amina Hadzalic, Klaus-Michael Debatin, Lukasz Winiarski, Jozef Oleksyszyn, Christian Rainer Wirtz, Uwe Knippschild, and Timo Burster. Diisothiocyanate-derived mercapturic acids are a promising partner for combination therapies in glioblastoma. ACS Omega. doi: 10.1021/acsomega.1c06169. IF: 3.512. SJR: 0.78, Q1
3. Fabian Gärtner, Adrian Gihring, Aileen Roth, Joachim Bischof, Pengfei Xu, Leonard Elad, Martin Wabitsch, Timo Burster, Uwe Knippschild. Obesity prolongs the inflammatory response in mice after severe trauma and attenuates the splenic response to the inflammatory reflex. Frontiers in Immunology. IF: 7.561. SJR: 2.65, Q1
4. Timo Burster, Zhadyra Mustafa, Dinara Myrzakhmetova, Anuar Zhanapiya, and Michal Zimecki. Hindrance of the proteolytic activity of neutrophil-derived serine proteases by serine protease inhibitors as a management of cardiovascular diseases and chronic inflammation. Frontiers in Chemistry. Invited Review. IF: 5.221. SJR: 1.03, Q1
5. Zhadyra Mustafa and Timo Burster. Comments on thrombosis after vaccination: The leader sequence of the spike protein might be responsible for thrombosis and antibody-mediated thrombocytopenia. Viral Immunology. Comment. Peer reviewed. IF: 2.257, SJR: 0.78, Q3
6. Timo Burster, Rebecca Traut, Zhanerke Yermekkyzy, Katja Mayer, Mike-Andrew Westhoff, Joachim Bischof, and Uwe Knippschild. Critical view of novel treatment strategies for glioblastoma: Failure and success of resistance mechanisms by glioblastoma cells. Frontiers Cell and Developmental Biology. Invited Review. doi: 10.3389/fcell.2021.695325. IF: 6.684, SJR: 2.45, Q1
7. Timo Burster, Fabian Gärtner, Christiane Bulach, Anuar Zhanapiya, Adrian Gihring, and Uwe Knippschild. Regulation of MHC I molecules in glioblastoma cells and the sensitizing of NK cells. Pharmaceuticals. Invited Review. doi: 10.3390/ph14030236. IF: 5.863, SJR: 1.3, Q1
8. Patricia Kattner, Katharina Zeiler, Verena J. Herbener, Katia La Ferla-Brühl, Rebecca Kassubek, Michael Grunert, Timo Burster, Oliver Brühl, Anna Sarah Weber, Hannah Strobel, Georg Karpel-Massler, Sibylle Ott, Alexa Hagedorn, Daniel Tews, Ansgar Schulz, Vikas Prasad, Markus D. Siegelin, Lisa Nonnenmacher, Pamela Fischer-Posovszky, Marc-Eric Halatsch, Klaus-Michael Debatin, Mike-Andrew Westhoff. What animal cancers teach us about human biology. Theranostics. Review. doi: 10.7150/thno.56623. IF: 11.556, SJR: 2.69, Q1
9. Zhadyra Mustafa, Anuar Zhanapiya, Hubert Kalbacher, and Timo Burster. Neutrophil elastase and proteinase 3 cleavage sites are adjacent of the polybasic sequence within the proteolytic sensitive activation loop of the SARS-CoV-2 spike protein. ACS Omega. doi: 10.1021/acsomega.1c00363. IF: 3.512 SJR: 0.78, Q1
10. Timo Burster, Fabian Gärtner, Uwe Knippschild, Anuar Zhanapiya. Activity-based probes to utilize the proteolytic activity of cathepsin G in biological samples. Feb. Frontiers in Chemistry. Invited Review. doi: 10.3389/fchem.2021.628295. IF: 5.221. SJR: 1.03, Q1
11. Fabian Gärtner, Uwe Knippschild, and Timo Burster. Application of an activity-based probe to determine proteolytic activity of cell surface cathepsin G by mass cytometry data acquisition. Oct 19;5(43). ACS Omega. doi: 10.1021/acsomega.0c04092. IF: 2.87 SJR: 0.77, Q1
12. Pengfei Xu, Fabian Gärtner, Adrian Gihring, Congxing Liu, Timo Burster, Martin Wabitsch, Uwe Knippschild, Stephan Paschke. Influence of obesity on remodeling of lung tissue and organization of extracellular matrix after blunt thorax trauma. Sep 17;21(1):238. Respiratory Research. doi: 10.1186/s12931-020-01502-0. IF: 3.89 SJR: 1.44, Q1
13. Herbener VJ, Timo Burster, Goreth A, Pruss M, von Bandemer H, Baisch T, Fitzel R, Siegelin MD, Karpel-Massler G, Debatin KM, Westhoff MA, Strobel H. Considering the experimental use of Temozolomide in Glioblastoma research. Biomedicines. Invited Review. doi: 10.3390/biomedicines8060151. IF: 4.717 SJR: 1.51, Q1
14. Timo Burster, Uwe Knippschild, Ferdinand Molnar, and Anuar Zhanapiya. Cathepsin G and its role in modulating levels of MHC class I molecules. 2020. Aug 19;68(4):25. Archivum Immunologiae et Therapiae Experimentalis (AITE). Invited doi: 10.1007/s00005-020-00585-3. IF: 2.85 SJR: 1.01, Q1
15. Bożena Obmińska-Mrukowicza, Marianna Szczypka, Aleksandra Pawlaka, Agnieszka Suszko-Pawłowska, Angelika Sysak, Aleksandra Zambrowiczb, Timo Burster, Maja Kociębad, Jolanta Artym, Ewa Zaczyńskad, Iwona Kochanowska, Michał Zimecki. Effects of yolkin on the immune response of mice and its plausible mechanism of action. 2020. Immunology Letters. doi: 10.1016/j.imlet.2020.01.003. IF: 2.552, SJR: 1.08, Q2
16. Roman Schroeder, Renata Grzywa, Christian Rainer Wirtz, Marcin Sienczyk, and Timo Burster. Application of a novel FAM-conjugated activity-based probe to determine cathepsin G activity intracellularly. 2020. 588, 113488. Analytical Biochemistry: Methods in the Biological Sciences. doi: 10.1016/j.ab.2019.113488. IF: 2.507, SJR: 0.63, Q2
17. Xu, Chiara Ianes, Fabian Gärtner, Congxing Liu, Johannes Lemke, Timo Burster, Vasiliy Bakulev, Najma Rachidi, Uwe Knippschild, Joachim Bischof. Regulation and functions of the stress-induced CK1 delta: A promising therapeutic target in neurodegenerative diseases and Cancer. doi: 10.1016/j.gene.2019.144005. Gene. Review. IF: 2.638, SJR: 0.91, Q1
18. Joachim Bischof, Fabian Gärtner, Katja Zeiser, Rebecca Kunz, Corinna Schreiner, Elena Hoffer, Timo Burster, Uwe Knippschild, and Michal Zimecki. Immune cells and immunosenescence. 2019. Folia Biologica. Review. PMID: 31464181. IF: 1.044, SJR: 0.35, Q3
19. Adriane Penczek and Timo Burster. Cell surface cathepsin G can be used as an additional marker to distinguish T cell subsets. 2019. Apr; 10 (4):245-249. Biomedical Reports. doi: 10.3892/br.2019.1198. IF: 1.8, SJR: 0.62, Q1
20. Lubos Marta, Dębowski Dawid, Barcinska Ewelina, Meid Annika, Inkielewicz-Stepniak Iwona, Timo Burster, and Rolka Krzysztof. Inhibition of human constitutive 20S proteasome and 20S immunoproteasome with novel N-terminally modified peptide aldehydes and their antitumor activity. 2019. e24100. DOI: 10.1002/pep2.24100. Peptide Science. IF: 1.969, SJR: 0.66, Q2

BIOL 341 Biochemistry I

BIOL 410 Immunology